Highly Specific Paper-based Detection of Neonatal Sepsis
Researchers at Purdue University have developed bench-top molecular biology detection into a portable and easy-to-use paper test strip. Assay time is decreased (less than 1.5 hours) by adjusting LAMP reagent concentration, and its high selectivity decreases the amount of false positives. In addition, this detection strip is within the amplification reaction itself and does not require downstream steps to perform detection. The paper effectively prepares, amplifies, and detects bacterial nucleic acids, such as E. coli, from infected whole-blood samples for rapid sample-to-answer disease detection.
Decreased assay timeDecreased false positivesEffective amplificationPortable/easy to use
Rapid disease detectionDiagnose sepsis in neonatal infants
Jacqueline LinnesLinnes LabPurdue Biomedical Engineering
United States
None
美国
