Method and Composition for Efficient Screening Cancer Metastasis Therapeutics
Possible commercial applications may include screening for actives that may reduce metastasis.
UC San Diego investigators have developed a method, nucleic acid construct and modified cells for efficient screening of actives that may be suitable metastasis therapeutics. Agents of interest, for example, potential cancer cell survival inhibitors or metastatic inhibitors, may be screened for a reduction in reporter or marker (e.g., luciferase, GFP) expression when the candidate agents are administered to cells comprising the nucleic acid construct. This may allow for rapid and efficient screening for new actives to inhibit metastasis.
Intellectual Property Info Patent application has been filed. Tech ID/UC Case 23980/2014-190-0 Related Cases 2014-190-0
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