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High through put screening for small molecules that inhibit the release of enveloped viruses from cells
技术优势
Potentially effective against a large host of pathogenic enveloped viruses because many enveloped viruses use the same mechanism to release particles from cells, including herpes viruses (HSV) , arena- (LFV, LCMV), filo- (EboV, MarV), flavi- (HCV), hepadna- (HBV), rhabdoviruses (VSV, RV), and some paramyxoviruses (SV5, MuV)Increases detection of infected cells by natural immune systemDecreases viral titer in plasma and decelerates the spread of infection Offers a period of time to protect the immune system and clear the infection
详细技术说明
Small molecules that block viral budding from infected cells #therapeutics #smallmolecule #drugdiscovery
国家/地区
美国
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