Larger Volume MRI
Accelerated Large Volume MRIA novel approach to magnetic resonance imaging (MRI) significantly accelerates the acquisition of large volume images. The approach consists of two different stages: contrast preparation followed by image encoding. The contrast preparation step uses a common contrast preparation module, which is subsequently “stored” in the longitudinal axis (parallel to the static field of the magnet, B0, along the z-axis), where it has a relatively long lifetime (in seconds). This longer lifetime allows the image encoding step to obtain rapid, consecutive, multislice coverage of the desired volume without further contrast preparation by using “slice” acceleration techniques such as multiband (MB), which is also known as Simultaneous Multi-Slice (SMS), simultaneous image refocused (SIR) and/or a combination of the two (“Multiplexed” imaging). Each of these “slice” acceleration techniques can also use conventional “in-plane” parallel imaging techniques like GRAPPA or SENSE to minimize acquisition time of each k-space coverage following RF excitation.Decreased MR Scan TimeSince their initial applications, fast acquisition sequences such as echo planar imaging (EPI) have not seen substantial improvements in overall scan time. While these approaches have decreased scan time for spatial encoding, with many consequent benefits, they have not significantly reduced image acquisition time required for volume coverage, because a physiological and/or anatomical contrast preparation period must precede the spatial encoding period for each slice; this contrast preparation period can equal or exceed the time for recording the echo train and must be repeated with each excitation. The new approach offers significant acceleration in image acquisition, a benefit in itself, increase temporal resolution, and may also increase patient throughput thus reducing costs. Furthermore, this technology may offer the ability to perform clinically relevant scans previously not possible due to the extended scan times or limits on heating of patient tissue (i.e. SAR).BENEFITS AND FEATURES:Substantial decrease in MR scan time for a variety of MRI techniquesMuch faster image acquisition (10x can be possible) without sacrificing SNR or spatial resolutionSpecifically provides acceleration beyond MB acceleration factorGreater temporal resolutionMay allow faster patient throughputMay allow scans previously not possible due to extended length of scan timesMay allow scans previously not possible due to SARAPPLICATIONS:MRI applicationsBrain imagingEcho planar imagingSpiral imagingVariety of MRI techniquesPhase of Development - Proofof Concept
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