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3-phosphoglycerate dehydrogenase (PHGDH) inhibitors
详细技术说明
The inventors have identified inhibitors for an enzyme, PHGDH, that is required for the synthesis of serine, which can be used to treat certain cancers.
其他
Identification of a smallmolecule inhibitor of 3-phosphoglycerate dehydrogenase to target serinebiosynthesis in cancers. Mullarky et al., PNAS 2016.
国家/地区
美国

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