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Disrupted Adenovirus-based Vaccine Against Drugs of Abuse

详细技术说明

This invention provides an adenovirus-antigen conjugate comprising (a) adisrupted adenovirus with a coat protein or an isolated or purified adenoviruscoat protein and (b) an antigen of the addictive drugs conjugated to theadenovirus coat protein, and a method for using such a conjugate to induce animmune response against the antigen in the human to treat drug abuse.

其他

Cocaine analog coupled to disrupted adenovirus: a vaccinestrategy to evoke high-titer immunity against addictive drugs. Mol. Ther. 2011, 19, 612-9.
Disruptedadenovirus-based vaccine against drugs of abuse. Published patent application WO2011116189 A1.

国家/地区

美国

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