亚洲知识产权资讯网为知识产权业界提供一个一站式网上交易平台，协助业界发掘知识产权贸易商机，并与环球知识产权业界建立联系。无论你是知识产权拥有者正在出售您的知识产权，或是制造商需要购买技术以提高操作效能，又或是知识产权配套服务供应商，你将会从本网站发掘到有用的知识产权贸易资讯。

返回搜索结果

Protein Knockout Platform

详细技术说明

Methods to eradicate proteins at mRNA and protein levelsKitscomprising engineered SCF ubiquitin ligase and corresponding siRNA

其他

Published US Patent Application US20130011920
Zhou P, et al Harnessing the ubiquitination machinery to target the degradation of specific cellular proteins. Mol Cell. 2000 Sep;6(3):751-6 (Pubmed 11030355)
Zhang J, Zheng N, Zhou P. Exploring the functional complexity of cellular proteins by protein knockout. PNAS. 2003 Nov 25;100(24):14127-32. (Pubmed 14593203)
Cong F e al. A protein knockdown strategy to study the function of beta-catenin in tumorigenesis. BMC Mol Biol. 2003 Sep 29;4:10. (Pubmed 14516475)
Cohen JC et al Transient in utero knockout (TIUKO) of C-MYC affects late lung and intestinal development in the mouse. BMC Dev Biol. 2004 Apr 16;4:4. (Pubmed 15090077)
Zhou P. Targeted protein degradation. Curr Opin Chem Biol. 2005 (Pubmed 15701453)

国家/地区

美国

欲了解更多信息，请点击这里