A Method for Manufacturing Potent Dendritic Cells
• Generation of a potent DC vaccine for treatment of cancer or infectious disease.• Generates DCs with greater potency than those produced by currently available methods.o Generation of potency is achieved through biological stimuli, circumventing the need for genetic vectors or prolonged cell selection.
Researchers at UCLA have developed a novel method for inducing dendritic cells (DCs) from monocytes. Compared to current methods, this innovation generates DCs with greater potency as antigen presenting cells for the activation of T cells. These potent DCs could be infused into cancer or infectious disease patients as part of a vaccine to enhance T cell activation.
Patent Number: WO2012142597A1
Application Number: WO2012US33811A
Inventor: MODLIN, Robert Lazarus | SCHENK, Mirjam
Priority Date: 15 Apr 2011
Priority Number: WO2012142597A1
Application Date: 16 Apr 2012
Publication Date: 18 Oct 2012
IPC Current: C12N0005071
Assignee Applicant: The Regents of the University of California
Title: A METHOD FOR GENERATING POTENT DENDRITIC CELLS | PROCÉDÉ POUR LA GÉNÉRATION DE CELLULES DENDRITIQUES PUISSANTES
Usefulness: A METHOD FOR GENERATING POTENT DENDRITIC CELLS | PROCÉDÉ POUR LA GÉNÉRATION DE CELLULES DENDRITIQUES PUISSANTES
Summary: The method is useful for inducing dendritic cell differentiation from a mammalian precursor cell (claimed).
生物医学
DNA /基因工程
9273284
Additional Technologies by these Inventors Tech ID/UC Case 22306/2011-562-0 Related Cases 2011-562-0
美国
