Peptide Mimotopes to Oxidation Specific Epitopes
In conjunction with different carriers, the newly identified peptides can be used as immunogens to study the mechanistic role of MDA-specific immune responses in immunization studies, and may provide the basis for potential atheroprotective vaccines, and could also be useful as imaging agents for inflammatory sites and/or atherosclerotic lesions.
UCSD researchers have identified two peptide mimotopes that form a three dimensional representation of critical epitopes of MDA. These mimotopes have been shown to be representative of oxidation-specific epitopes that are proinflammatory and proatherogenic.
化工/材料
化工/材料应用
Tech ID/UC Case 22613/2012-183-0 Related Cases 2012-183-0
美国
