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Hybrid Flagellin as a Novel T Cell Independent Vaccine Scaffold


技术应用

This hybrid flagellin vaccine scaffold may be used to vaccinate individuals with less robust immune systems, including those in the early perinatal period, in people suffering from various T cell immunodeficiency disorders (HIV-AIDS, DiGeorge syndrome), patients undergoing chemotherapy, as well as elderly patients with sluggish adaptive immunity.


详细技术说明

None


申请号码

20180169205


其他

Other Information

Related Publication:

Bennett, K. M. et al. Hybrid Flagellin as a T Cell Independent Vaccine Scaffold. BMC Biotechnol. 15, 71 (2015).


Images

hiFLC forming stable filaments


Background

Vaccines are biological products that are able to establish resistance to specific antigens (diseases) in our bodies, through stimulating the immune system and creating antibodies. While traditional types of vaccines are based on weak live virus, killed virus or bacteria, newer versions are toxoid-based, or genetically engineered (including engineered microbes, subunit vaccines, conjugate vaccines, DNA vaccines, and vector vaccines).  Vaccines have a total market size of around $32 billion (2016). This market is estimated to reach the level of nearly $48 billion by 2021, resulting in a compound annual growth rate (CAGR) of 8.3%.


Tech ID/UC Case

24323/2014-912-0


Related Cases

2014-912-0


国家/地区

美国

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