Self-Regulating CD Microfluidic System
This microfluidic device may be used for integrated centrifugal microfluidic sample preparation. It also may be used for cellular and chemical analysis along with clinical and medical diagnostic applications.
The microfluidic device has a number of microfluidic elements or features (e.g., reservoirs, chambers, channels and the like) that are utilized on a CD and connected to each other by ventilation channels and fluid transfer channels. This self-regulating device avoids the problem of cross-contamination. The system accomplishes this by negative feedback. Any excess fluid will enter into the ventilation channels to stop fluid transfer from the starting chambers. Such starting chambers may contain a lysing agent or processing fluid. The excess fluid is prevented from entering into an output chamber that would mix with the fluids from the starting chambers. However with the CD undergoing a higher RPM, the fluid may be transferred from the starting chambers to the output chambers.
Patent Number: US20090061229A1
Application Number: US2008204763A
Inventor: Earthman, James C. | Mohamed, Farghalli A. | Mishra, Rahul K. | Roy, Indranil
Priority Date: 4 Sep 2007
Priority Number: US20090061229A1
Application Date: 4 Sep 2008
Publication Date: 5 Mar 2009
IPC Current: B32B000516 | B22F000902 | B22F000904 | C22C000110
US Class: 428402 | 075252 | 241023
Assignee Applicant: The Regents of the University of California
Title: DIAMONDOID STABILIZED FINE-GRAINED METALS
Usefulness: DIAMONDOID STABILIZED FINE-GRAINED METALS
Summary: A stabilized metal or metal composition, preferably a stabilized cryomilled nanocrystalline aluminum (claimed).
Novelty: Stabilized metal or metal composition, preferably stabilized cryomilled nanocrystalline aluminum, comprises nanocrystalline metal particles and diamantane particles
化工/材料
化工/材料应用
8124030
State Of Development A prototype has been made. Testing The prototype has been shown to effectively transfer and mix fluids without cross-contamination. Tech ID/UC Case 24074/2007-201-0 Related Cases 2007-201-0
美国
