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Compositions and Methods for the Treatment of Respiratory Conditions via NKG2D Inhibition


技术优势

antibody or protein therapy effective at the cellular leveldecreased possibility of side effects due to high selectivity and identification of a specific targetsuitable for treating a number of respiratory conditions, including asthma, steroid-resistant asthma and COPD


技术应用

treating or preventing respiratory conditions such as asthma, steroid-resistant asthma, and COPD


详细技术说明

None


附加资料

Patent Number: WO2013032943A1
Application Number: WO2012US52369A
Inventor: RAULET, David | HAWORTH, Oliver | LOCKSLEY, Richard | BORCHERS, Michael
Priority Date: 26 Aug 2011
Priority Number: WO2013032943A1
Application Date: 24 Aug 2012
Publication Date: 7 Mar 2013
IPC Current: A61K0039395 | A61K004800 | A61P001100 | A61P001106
Assignee Applicant: The Regents of the University of California
Title: METHODS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY CONDITIONS VIA NKG2D INHIBITION | PROCÉDÉS ET COMPOSITIONS POUR LE TRAITEMENT DE PATHOLOGIES RESPIRATOIRES PAR INHIBITION DE NKG2D
Usefulness: METHODS AND COMPOSITIONS FOR THE TREATMENT OF RESPIRATORY CONDITIONS VIA NKG2D INHIBITION | PROCÉDÉS ET COMPOSITIONS POUR LE TRAITEMENT DE PATHOLOGIES RESPIRATOIRES PAR INHIBITION DE NKG2D
Summary: The method, composition, and kit are useful for treating or preventing a respiratory condition, where the respiratory condition is asthma or chronic obstructive pulmonary disease (COPD) (all claimed).
Novelty: Treating or preventing a respiratory condition comprises administering to the subject a composition comprising an inhibitor of killer cell lectin-like receptor subfamily K, member 1 (NKG2D)-mediated activation of leukocytes


主要类别

生物医学


细分类别

医药成分


申请号码

20140248289


其他

Publication

NKG2D Mediates NK Cell Hyperresponsiveness and Influenza-Induced Pathologies in a Mouse Model of COPD


Tech ID/UC Case

22499/2012-099-0


Related Cases

2012-099-0


国家/地区

美国

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