Resorbable Injectable Hydrogel for Bone Repair and Tissue Engineering
Ability to control speed of gelation Ability to control resorption time in situ Stimulates repair while degrading into resorbable componentsTested in dog, sheep and horse animal models
Bone injury repair in mammals
Hydrogels are being developed for a broad range of applications, including tissue repair. One beneficial feature of many hydrogels is that they are injectable, allowing the non-invasive delivery of the hydrogel to the targeted tissue. Researchers at the University of California, Davis, have developed a resorbable injectable hydrogel composed of natural polymers that promotes tissue repair in mammals and has been successfully tested in horse, sheep and canine subjects. The polymers are chemically enhanced to enable cell adhesion and promotion of cell survival within the gel. The composition has allowed researchers to control the speed of gelation as well as resorption time in situ. As a composite, this injectable vehicle is advantageous over gels prepared from a single constituent. The hydrogel capitalizes on the benefits of each individual constituent, stimulating repair while degrading into resorbable components.
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Additional Technologies by these Inventors Tech ID/UC Case 23954/2012-198-0 Related Cases 2012-198-0
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