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Efficient Synthesis of HIV-1 Protease Inhibitors
总结
Researchers at Purdue University have developed a new series of hexahydrofuropyran-derived HIV-1 protease inhibitors for treatment of HIV infection and AIDS. These inhibitors are novel and remarkably potent, similar to Darunavir, an FDA approved inhibitor also developed at Purdue. They also show excellent activity against multiple PI-resistant variants, superior to other FDA approved inhibitors.
技术优势
High antiviral potencyEffective against wide range of variants
技术应用
Medical/HealthcarePharmaceuticalsHIV/AIDS TreatmentDrug Development
详细技术说明
Arun GhoshGhosh GroupPurdue Chemistry
国家
United States
申请号码
9,024,038
国家/地区
美国
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