Synthesis and Design of Silver Nanoparticle Embedded mPEG-PDLLA Polymersome Nanocarriers
The nanocarrier:ΓÇóAllows for combination of multiple drugs into one system, enabling effective treatment of complex infectionsΓÇóProvides a long lasting and time release treatment as compared to conventional systemsΓÇóHelps in effectively overcoming bacterial genetic resistance to antibioticsΓÇóAllows for release of antibiotics over several weeks, reducing the number of dosages as well as infection relapse potentialΓÇóEnables a reduced antibiotic degradation as compared to conventional systemsΓÇóAllows for an ideal particle size, enabling desirable retention time within the biological systemΓÇóWould be commercially useful for the following applications:oTreatment of life-threatening infections especially related to antibiotic resistant bacteriaoReduction in spread of bacterial generic resistance against antibioticsoElimination of persistent infectionsoMedical device/implant coatings for reducing medical device-related infections
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