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1,2,4-TRIAZOLE DERIVATIVES WITH CANNABINOID PROPERTIES


详细技术说明

None


附加资料

Patent Number: WO2003082833A1
Application Number: WO2003ES126A
Inventor: JAGEROVIC, Nadine | GOYA LAZA, María, Pilar | HERNÁNDEZ FOLGADO, Laura | ALCORTA OSORO, Ivon, José | MARTIN FONTELLES, María, Isabel | SUARDIAZ GARCÍA, Margarita, Linarejos | DANNERT, María, Teresa
Priority Date: 27 Mar 2002
Priority Number: WO2003082833A1
Application Date: 18 Mar 2003
Publication Date: 9 Oct 2003
IPC Current: A61K00314196 | C07D024908 | C07D040104
Assignee Applicant: Consejo Superior De Investigaciones Científicas | Universidad Rey Juan Carlos
Title: 1,2,4-TRIAZOLE DERIVATIVES WITH CANNABINOID PROPERTIES | DERIVADOS DE 1,2,4-TRIAZOL CON PROPIEDADES CANNABINOIDES. | DERIVES DE 1,2,4-TRIAZOL POSSEDANT DES PROPRIETES CANNABINOIDES
Usefulness: 1,2,4-TRIAZOLE DERIVATIVES WITH CANNABINOID PROPERTIES | DERIVADOS DE 1,2,4-TRIAZOL CON PROPIEDADES CANNABINOIDES. | DERIVES DE 1,2,4-TRIAZOL POSSEDANT DES PROPRIETES CANNABINOIDES
Summary: (I) are used as medicaments for combating disorders involving cannabinoid receptors, specifically for the treatment or prevention of glaucoma, bronchial asthma, chronic bronchitis, allergies (e.g. contact dermatitis or allergic conjunctivitis), arthritis, pain, organ transplant problems, motor disorders associated with Tourette syndrome, Parkinson's disease, Huntington's chorea, malignant glioma, multiple sclerosis, emesis associated with anticancer chemotherapy, eating disorders, acute schizophrenia and cognitive and memory dysfunction associated with Alzheimer's disease (all claimed). (I) are especially useful for reducing appetite, reducing dyskinesia caused by L-DOPA in Parkinson's disease patients, treating acute schizophrenia and treating cognitive and memory dysfunction associated with Alzheimer's disease.
Novelty: New 1-benzyl or 1-phenyl-1H-1,2,4-triazole derivatives having cannabinoid properties, useful e.g. for treating asthma, bronchitis, allergy, arthritis, pain, Parkinson's disease, eating disorders or schizophrenia


主要类别

生物医学


细分类别

DNA /基因工程


国家/地区

美国

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