Graphene Nanomesh As A Glucose Sensor
- 技術優勢
- High sensitivity, sensitivity, and fast response speed The ambipolar field characteristic of graphene sensors enables the detection of both positively and negatively charged species Free of “oxygen deficit” problem
- 技術應用
- Monitor blood glucose concentration in diabetes care In vivo glucose sensing
- 詳細技術說明
- Researchers at UCLA have developed a novel glucose sensing mechanism based on the doping effect of H2O2 to GNM. They have demonstrated the capability of GNM-based field effect transistor devices as an effective glucose sensor, and also solved the “oxygen deficit” problem since nanoscale GNM glucose sensor consumes little oxygen due to its small size. Meanwhile, the exceptionally high carrier mobility and large surface to volume ratio of graphene-based sensors provide these new glucose sensors with high sensitivity and fast response speed.
- *Abstract
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UCLA researchers in the Departments of Chemistry & Biochemistry and of Materials Science & Engineering have developed a glucose sensor based on a graphene nanomesh (GNM) material. The nanoscale GNM glucose sensor provides the potential for in vivo glucose sensing with high selectivity and high sensitivity.
- *Principal Investigation
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Name: Jingwei Bai
Department:
Name: Rui Cheng
Department:
Name: Xiangfeng Duan
Department:
Name: Yu Huang
Department:
Name: Shan Jiang
Department:
- 其他
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State Of Development
The proposed glucose sensing mechanism has been tested.
Background
A GNM consists of a single or few-layers of graphene with a high density periodic array of nanoholes punched in. This unique structure of GNM overcomes several limitations of graphene, leading to appreciable band gap and transconductance at room temperature as well as higher functional group density, making it a promising material for graphene-based chemical sensor and biosensor applications.
Currently, most glucose sensors are based on electrochemical reactions by using amperometric enzyme electrodes. These glucose sensors rely on the detection of hydrogen peroxide generated by glucose oxidase catalyzed redox reaction through amperometric electrodes, and they tend to have relatively low selectivity because the anodic current can be introduced by oxidation of other chemicals in the environment. They also suffer from “oxygen deficit,” as the performance of the sensor is subject to errors caused by fluctuation of oxygen tension if oxygen is not in non-rate limiting excess after consumption by the glucose oxidase catalyzed reaction. Another type of glucose sensor utilizes an electron mediator which shuttles electrons between the electrode and enzyme as a substitute of oxygen. However, the mediator is usually toxic and the sensor is not appropriate to work in vivo.
Additional Technologies by these Inventors
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- A Composite of Two Dimensional Material and One Dimensional Material as Transparent Conductor
- Conductor-Semiconductor Composite Films and Their Applications for High Performance Transistors
- Chemical Vapor Deposition Growth of the Large Single Crystalline Domains of Monolayer and Bilayer
- Graphene Based Catalysts for Biomimetric Generation of Antithrombotic Species
- Palladium Alloy Hydride Nano Materials
- High Performance Thin Films from Solution Processible Two-Dimensional Nanoplates
- Nanoscale Optical Voltage Sensors
- Ultrafine Nanowires As Highly Efficient Electrocatalysts
- Pore Size Engineering Of Porous Carbons Using Covalent Triazine Frameworks As Precursors
- The Method of Enhanced Pressure Sensing Performance for Pressure Sensors
- Very High Energy Density Silicide-Air Primary Batteries
- Wafer Scale Growth Of Large Arrays Of Perovskite Micro-Plate Crystals For Functional Electronics And Optoelectronics
- Three-Dimensional Holey Graphene Frameworks Based High-Performance Supercapacitors
- High Performance PtNiCuMo Electrochemical Catalyst
- Upconversion Plasmonic Mapping: A Direct Plasmonic Visualization And Spectrometer-Free Sensing Method
- Electrochemical Molecular Intercalation for Synthesis of Monolayer Atomic Crystal Molecular Superlattices
Tech ID/UC Case
29407/2011-419-0
Related Cases
2011-419-0
- 國家/地區
- 美國
