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Micropatterned Silicone Oxygenating Dressing For Chronic Wounds

詳細技術說明

Project ID: D2018-09 Background Wound healing requires oxygen, moisture, and pressure offloading. It is difficult to simultaneously obtain these conditions because oxygen has a low diffusivity in water. Hyperbaric oxygen therapy (HBOT) is an approved treatment which uses a pressurized chamber to increase oxygen absorption. However, patients must be ambulatory and complete a series of 30-60 sessions, each lasting about 2 hours. Additionally, HBOT chambers are not available everywhere and treatments cost between $15,000 and $40,000 over the duration of the treatment. Therefore, there is a need for an affordable and mobile treatment option to treat chronic wounds.  Invention DescriptionResearchers at the University of Toledo have developed a wound dressing capable of oxygen diffusion while still maintaining the moist environment ideal for healing. A microfabricated oxygen-permeable material is specially designed to maximize oxygen delivery.    Applications•       Oxygenating dressing for chronic wounds •       Available to those who are not eligible for hyperbaric treatment  Advantages•       Available to those who are not eligible for hyperbaric treatment or immobile•       Can be used in the comfort of a patient’s home and therefore, extend the treatment beyond two hours•       Does not require the use of deep reactive ion etching/expensive manufacturing methods•       More affordable than HBOT  IP Status:       Patent Pending  Publication:       Jaeger A, Das D, Morgan N, Pursley R, McQueen P, Hall M, Pohida T, Gottesman M.  Microfabricated polymeric vessel mimetics for 3-D cancer cell culture Biomaterials. 2013 Nov; 34(33): 8301-8313.

*Abstract

*Principal Investigation

Name: Chandan Das, Resident

Department: Surgery

Name: Munier Nazzai, Professor

Department: Surgery

Name: F. charles Brunicardi, Chairman

Department: Surgery

國家/地區

美國