亞洲知識產權資訊網為知識產權業界提供一個一站式網上交易平台，協助業界發掘知識產權貿易商機，並與環球知識產權業界建立聯繫。無論你是知識產權擁有者正在出售您的知識產權，或是製造商需要購買技術以提高操作效能，又或是知識產權配套服務供應商，你將會從本網站發掘到有用的知識產權貿易資訊。

返回搜索結果

Stem Loop RNA Mediated Transport of Mitochondria Genome Editing Molecules (Endonucleases) into the Mitochondria

詳細技術說明: Inventors at Nationwide Children's Hospital have developed a novel system for importing the CRISPR/Cas9 system into the mitochondria for editing of mtDNA.

*Abstract: Pathogenic mutations and deletions in the maternally inherited mitochondrial genome (mtDNA) affect as many as 1/500 births and have poor prognosis for treatment. While the CRISPR/Cas9 system for genomic editing has created a new platform for treatment of genetic diseases, researchers have yet to apply the system to mtDNA due to the challenges of transport into the mitochondria. Inventors at Nationwide Children's Hospital have developed a novel system for importing the CRISPR/Cas9 system into the mitochondria for editing of mtDNA.

*Inquiry: Kyle Murrah, Ph.D. The Research Institute at Nationwide Children's Hospital Office of Technology Commercialization 700 Children's Drive Columbus OH 43205 T: 614 355-4551 F: 614 722-2716 Kyle.Murrah@nationwidechildrens.org

欲了解更多信息，請點擊這裡