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Chronic Sequential Sensorimotor Neural Probe Array

詳細技術說明
None
*Abstract

As of 2007, there are roughly 2 million individuals living with major limb loss (excluding fingers and toes) in the United States and every year there are more than 185,000 new amputations. Additionally, it is estimated that between 200,000 and 450,000 Americans are currently living with spinal cord injury, though that number is commonly believed to be under-reported. There is a large unmet need for an effective chronic interface between nervous tissue and prosthetic devices.

The useable life of currently employed neural probes is typically less than one year due to a variety of factors including: scar formation or tissue encapsulation around the probes, dislocation, probe deterioration, severed nerve regression (displacement) and other factors.

University of California researchers have developed a micro-implantable device (Chronic Sequential Neural Probe Array) that interfaces with peripheral nerves chronically. The device can be used to both sense and stimulate the never fiber when triggered with an external controller. In addition, the device (probe array) is designed to store drugs in a series of micro chambers for the delivery of the drug to the nerve. The drugs can be used to extend the viability of the nerve and probe array by limiting the formation of scar tissue and the resulting loss of potential at the electrode. Further, the device contains a series of arrays that, each of which can be deployed to interface with the target nerve when the function of the previous array has deteriorated.

The Chronic Sequential Neural Probe Array is designed for patients with an axonal injury in the peripheral nerves or spinal cord who require chronic intervention where stimulation of and/or recording from the axonal bundles is desired. There are two major categories of potential patients: those dealing with paralysis and those dealing with spinal cord injury (SCI) or amputation.

*IP Issue Date
May 28, 2013
*Principal Investigation

Name: William Bunney, Jr.

Department:


Name: James Fallon

Department:


Name: Ryan Langan

Department:


Name: William Tang

Department:

附加資料
Patent Number: US20120323102A1
Application Number: US13164599A
Inventor: Tang, William C. | Fallon, James H. | Bunney, William E. | Langan, Ryan
Priority Date: 20 Jun 2011
Priority Number: US20120323102A1
Application Date: 20 Jun 2011
Publication Date: 20 Dec 2012
IPC Current: A61B000504 | A61N000105
US Class: 600377 | 607118
Assignee Applicant: The Regents of the University of California
Title: NEURAL PROBE ARRAY AND METHOD OF USE
Usefulness: NEURAL PROBE ARRAY AND METHOD OF USE
Summary: Probe device for stimulating and sensing electrical signals in nerve fibers of a patient or amputees to treat paralysis.
Novelty: Probe device for stimulating and sensing electrical signals in nerve fibers of patient or amputees to treat paralysis, has actuatable, moveable electrodes placed in housing along length of nerve fibers
主要類別
生物醫學
細分類別
醫療裝置
申請號碼
8452418
其他

Tech ID/UC Case

22178/2008-475-0


Related Cases

2008-475-0

國家/地區
美國

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