亞洲知識產權資訊網為知識產權業界提供一個一站式網上交易平台，協助業界發掘知識產權貿易商機，並與環球知識產權業界建立聯繫。無論你是知識產權擁有者正在出售您的知識產權，或是製造商需要購買技術以提高操作效能，又或是知識產權配套服務供應商，你將會從本網站發掘到有用的知識產權貿易資訊。

返回搜索結果

Fluorescent Probes For Detection Of Copper In Cells And Living Organisms

技術應用: - Diagnostics and determination of treatment efficacy in human patients- Animal models for genetic and neurodegenerative diseases- Detection of basal levels of copper- Long-term experiments with copper levels monitoring (e.g. aging and dietary studies)

*Abstract: Copper is involved in the development and progression of many diseases, including Menkes disease, Wilsons disease, neurodegenerative diseases, anemia, heart disease, and cancer. Furthermore, copper is a well-known metal cofactor in many enzymes and is necessary for proper cellular function. Therefore, there is a great demand for systems that can be used to detect and study copper in both cells and, more importantly, living organisms.

Scientists at UC Berkeley have developed multiple molecular sensors for the detection of copper that are based on fluorescent scaffolds. In the absence of copper, these fluorescent sensors have little or no fluorescent signal following excitation by a light source. However, in the presence of copper, these fluorescent copper sensors emit light in the near-infrared region of the electromagnetic spectrum, making them ideal for in vivo imaging because they circumvent issues of autofluorescence and signal attenuation by tissue.

*Principal Investigation: Name: Christopher Chang
Department:

Name: Tasuku Hirayama
Department:

Name: Genevieve Van de Bittner
Department:

Name: Jefferson Chan
Department:

其他

Additional Technologies by these Inventors

Tech ID/UC Case

21190/2011-060-0

Related Cases

2011-060-0

欲了解更多信息，請點擊這裡