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Low-tech, minimally invasive localized brain drug delivery system

總結
Elisa Konofagou, Ph.D.
技術優勢
Utilizes intermediate frequencies to minimize damage to non-target regions and ultrasound aberrationsMRI-independent targeting and verificationMore compact than conventional technology allowing portability and increasing patient base to non-specialized clinical settings (e.g., outpatient clinics; community hospitals).Utilizes a single transducer setup, reducing the cost and targeting uncertaintyPatent information:Patent Pending (WO/2011/153268Tech Ventures Reference: IR CU14052
技術應用
Safe and reliable method to open the BBB in specific, shallow, or deep-seated brain regionsSpatially specific neuroscience research in a laboratory settingMay be adapted to improve accessibility and spatial resolution of ultrasound-hemostasis, -lithotripsy, and -assisted thrombolysis.May be adapted for non-invasive research of structures
詳細技術說明
Elisa Konofagou, Ph.D.
*Abstract
None
*Inquiry
Satish RaoColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu
*IR
CU14052
*Principal Investigation
*Publications
Marquet F, Tung Y, Teichert T, Ferrera VP, Konofagou EE. "Noninvasive, transient and selective blood-brain barrier opening in non-human primates in vivo" PLOS One. 2011 Jul 22;6(7):e22598.
國家/地區
美國

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