Nkx3.1/Pten Mutant Mice for the Study of Prostate Carcinogenesis
- 技術優勢
- These mice provide a model system for the study of the early stages of human prostate carcinogenesis
- 技術應用
- The study of prostate carcinogenesisCharacterization of the early stages of carcinogenesisDevelopment of potential treatments for prostate cancer
- 詳細技術說明
- The Nkx3.1 homeobox gene has restricted expression in the prostate and essential role in prostate differentiation and function. PTEN represents a frequent target of mutational inactivation in human cancers, and Pten heterozygous mutant mice develop c...
- *Abstract
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None
- *Inquiry
- Peter GolikovColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu
- *IR
- 2737
- *Principal Investigation
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- *Publications
- Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis. Kim, MJ et al. (2002) PNAS. 99(5): 2884-2889
- 國家/地區
- 美國
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