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A Method for Constructing Flow Constrictions Inside Microfluidic Channels

詳細技術說明
This technology enables microfluidic devices to be constructed more cost-efficiently.
*Abstract

A necessary function for microfluidic devices used in biology is the ability to "hold" a cell or other object (e.g., embryo) is a known physical location while maintaining the flow around it. This is particularly useful in bioproduction and applications such as incubation/maturation, infection, fertilization, or chemical treatment of a biological object. Although lithographic etching can be used to construct the holding areas (i.e., constriction regions), this method is expensive and complex. This technology uses a simple and inexpensive method — polymerization — to construct flow constriction regions. A prepolymer mixture is flowed into the microfluidic channel and polymerized using an ultraviolet source. As it is polymerized, the polymer shrinks, creating a small gap at the top of the channel. This gap, allows the fluid flow to continue while the cell/object is held in place. Thus, this technology enables microfluidic devices to be constructed more cost-efficiently. 

For more information about this technology, please contact the University of Illinois at Urbana-Champaign Office of Technology Management at otm@illinois.edu.

*IP Issue Date
None
*IP Type
Utility
國家
United States
申請號碼
7111635
國家/地區
美國

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