Microfabricated Fluid Channels
- 詳細技術說明
- Designed to eliminate the time-consuming dipping required for inking the dip pen nanolithography (DPN) array used for nanoscale patterning, this invention provides a method for providing fluids "inks" to a large array of scanning probe microscope tips.
- *Abstract
-
Designed to eliminate the time-consuming dipping required for inking the dip pen nanolithography (DPN) array used for nanoscale patterning, this invention provides a method for providing fluids "inks" to a large array of scanning probe microscope tips. The proprietary technology creates a high-density micropipette array with embedded microfluid channels and arrayed inking openings capable of simultaneously providing multiple types of chemical and biological solutions to closely spaced probes. Dip Pen Nanolithography (DPN) utilizes the capability of Scanning Probe Microscopy (SPM) technology to deposit chemicals onto substrate with sub-100-nm line width by coating the tip with a chemical of interest. The throughput of SPM-based nanolithography methods can be increased by using arrays of probes, in one- or two dimensions. Certain future applications require inking different tips with different chemicals. This invention provides a method for providing multiple types of chemical and biological solutions to closely spaced probes by creating a high-density micropipette array with embedded microfluidic channels and arrayed inking openings.
DESCRIPTION/DETAILS
This new method provides different inks to a large array of closely spaced scanning probe microscope tips. A microfluidic architecture enables the distribution of various fluids (inks) to a very closely packed inking well array. The architecture involves a system of embedded channels and fluid inlet reservoirs. Embedded channels distribute fluids (inks) and the fluid inlet reservoirs are designed with larger diameters and spacing than the inking openings. A preferred method for forming high density micropipettes using a simple microfabrication process is also disclosed.
APPLICATIONS
- Biotechnology: biochips, gene chips, protein chipsSemiconductors: microelectronic components
- Pharmaceuticals: research and development of new drugs
This new companion technology for the DPN multiple pen array allows the placement of unique "inks" on each probe tip for application in high-density DNA and protein arrays. Elimination of the time required for the DPN device to collect ink makes the nanoscale patterning process faster and more commercially viable. The technology also has the potential to reduce the use of expensive assay material and reduce the delay time created by the inking cycle itself.
For more information about this technology, please contact the University of Illinois at Urbana-Champaign Office of Technology Management at otm@illinois.edu.
- *IP Issue Date
- None
- *IP Type
- Utility
- 國家
- United States
- 申請號碼
- 7217396
- 國家/地區
- 美國
