亞洲知識產權資訊網為知識產權業界提供一個一站式網上交易平台，協助業界發掘知識產權貿易商機，並與環球知識產權業界建立聯繫。無論你是知識產權擁有者正在出售您的知識產權，或是製造商需要購買技術以提高操作效能，又或是知識產權配套服務供應商，你將會從本網站發掘到有用的知識產權貿易資訊。

返回搜索結果

Improved Retroviruses for Gene Therapy

總結: Researchers at Purdue University have developed a technology that allows quantitative measurement of virus entry into host cells and determination of the effectiveness of reagents that inhibit entry. This technology also allows for the production of Ebola glycoprotein-pseudotyped retroviruses with markedly improved titers, making the practical use of such viruses more feasible.

技術優勢: Allows gene therapy of the lung using pseudotyped retrovirusesImproved safety and efficiency

技術應用: Medical/HealthcarePharmaceuticalsDrug DevelopmentAntiviralsGene/Cell Therapy

*Background: Transducing cells with viral vectors to deliver novel nucleic acids requires a specific ligand or envelope glycoprotein on the virus surface to bind to a receptor on a target cell. By changing the ligand on the virus (pseudotyping), it is possible to enhance the transduction efficiency towards target cell types. For this technology, Ebola glycoprotein-pseudotyped retroviruses were produced for gene transduction into the lung and other tissues and for the study of Ebola virus entry into cells.

*Web Links: Purdue Office of Technology CommercializationPurdueInnovation and EntrepreneurshipDavid SandersDavid Sanders LabPurdue Biological Sciences

欲了解更多信息，請點擊這裡