Nanoscale Subsurface Imaging Method via SNFUH
- 技術優勢
- Nano-scale spatial resolutionNondestructive, real-space imagingAmenable to different material systemsProviding depth information
- 詳細技術說明
- Anovel nondestructive imaging method (SNFUH) providing nanoscale spatial resolution as well as depth information for embeddedstructural features.#medicaldevice #imaging #equipment #researchtool #method #photonics #holographic
- *Abstract
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Thereis an increasing need for nondestructive high-resolution imaging of various“buried” nano/micro-structures in scientific research andnano/micro-manufacturing process. To fill thiscritical void, a novel acoustic holography technology, known as thescanning near-field ultrasound holography (SNFUH), has been developed atNorthwestern to providenondestructive real-space imaging of embedded features with nanoscale lateral resolutionand depth sensitivity. This inventionis based on aunique integration of scanning probe microscope (SPM) platform coupled tomicroscale ultrasound source with novel detection and holography techniques. The ultrasound wave needed for this imaging technologyis generated during the thermal expansion of the samples that absorb the coherentlaser beam provided. Significantly outperforming alternativeapproaches (e.g. AFM) in imaging resolution, SNFUH is equally amenable to hard(e.g. semiconductor), soft (e.g. polymers and biological system), and hybridmaterials. This promising technologyoffers a versatile tool for numerous imaging and structure detectionapplications in physical sciences, engineered systems, and biology.
Figure Nanoscaleimaging of surface using SNFUH and comparison with AFM. (a):Schematic illustration of the SNFUH approach. (b, c): For a system with goldnanoparticle buried under a polymer surface, a typical AFM topography imageshows a featureless top polymer surface, whereas SNFUH clearly reals the buriednanoparticle with high definition. (d, e): SNFUH clearly reveals the internalstructural defect as the buried voids, whereas AFM only shows the top coating.(f, g): For a biological sample of red blood cells (RBCs) infected with malariaparasites, AFM shows the typical surface feature of RBCs, in contrast withSNFUH revealing the inside parasites with nanoscale resolution.
- *Inventors
- GajendraS. Shekhawat*VinayakP. Dravid
- *Publications
- Shekhawat GS, Dravid VP (2005) Nanoscale Imaging of Buried Structures via ScanningNear-Field Ultrasound Holography, Science, 310: 89-92.
- 國家/地區
- 美國
