Use of gOBG Polypeptides to Promote Increases in Muscle Mass and Muscle Differentiation
- 詳細技術說明
- None
- *Abstract
-
Whitehead Institute Intellectual Property Office is seeking a licensee for the invention "Use of ACRP30 Globular Head to Promote Increases in Muscle Mass and Muscle Differentiation". Researchers have found that daily administration of a very low dose of gAcrp30 (the murine homolog of Apm1 protein, generically referred to as OBG3) to mice consuming a high fat/sucrose diet caused profound and sustainable weigh reduction without affecting food intake. This invention concerns the novel effects of gAcrp30 on muscle cells, specifically the increase in oxidation of free fatty acids as well as the acceleration of muscle re-orientation and differentiation. This technology may be potentially therapeutic to muscle-related diseases or disorders such as the muscle-related disorders of aging and muscular dystrophy.
- 國家/地區
- 美國
