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Methods for PET/CT artifact correction using data emission data consistency

詳細技術說明

None

*Abstract

The integration of positron emission tomography (PET) and Xray computed tomography (CT) into a single instrument allows acquisition of functional and structural images that are spatially registered. This provides the opportunity to use the CT data from a combined scan for attenuation correction of the PET data. An advantage to this method of attenuation correction is that CT produces an image of exceptionally high statistical quality compared to either the emission data or to transmission data obtained with an external gamma source. One cause of deficiencies is the presence of IV or oral contrast agent administered to enhance the CT scan. Focal contrast artifacts in the resulting attenuation corrected emission images have been observed that resemble diseased tissue. Additionally, extended artifactual regions have been observed in the case of oral contrast agents. The hypothesis of this research program is that the measured emission sinograms contain sufficient attenuation information to allow correction of some deficiencies in the attenuation map. Researchers have investigated, with only limited success the problem of reconstructing the full attenuation map using only emission data. The goal of the proposed research is to develop, implement, and test methods for recovering only limited regions that are suspected of being inaccurate within an otherwise ideal attenuation map. This is a far simpler problem than the general case of generating a complete attenuation image with only emission data. An additional simplification arises if constraints can be imposed on the attenuation image. This program is in the early stages of algorithm development

*Principal Investigation

Name: Charles Laymon, Research Assistant Professor

Department: Med-Radiology

國家/地區

美國