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Method of Synthesis of Amphiphilic Magnetic Composite Particles

總結: Amphiphilic, magnetic composite particles are comprised of cores and shells. The core contains both hydrophobic vinylic graft copolymer, hydrophobic vinylic homopolymer and magnetic nanoparticles, and the shell to which the hydrophobic vinylic polymer is grafted is a hydrophilic, nitrogen-containing polymer. Typically, the composite particles are made by a process which involves generating radicals on nitrogen atoms of the water-soluble polymer, and then initiating free-radical copolymerization of said vinylic monomer(s) and vinylic-coated magnetic nanoparticles, whereby vinylic polymer(s) undergo(es) phase separation and the vinylic coated magnetic nanoparticles are encapsulated within the vinylic polymer to form a composite latex.

附加資料: Patent Number: US8404347B2
Application Number: US2009359393A
Inventor: Li, Pei | Ho, Kin Man
Priority Date: 26 Jan 2009
Priority Number: US8404347B2
Application Date: 26 Jan 2009
Publication Date: 26 Mar 2013
IPC Current: B32B001502 | B05D000702 | C08K000900
US Class: 428407 | 427222 | 42840224 | 428403 | 428404 | 428405 | 523201 | 523209 | 523210
Assignee Applicant: The Hong Kong Polytechnic University
Title: Method of synthesis of amphiphilic magnetic composite particles
Usefulness: Method of synthesis of amphiphilic magnetic composite particles
Summary: The amphiphilic magnetic composite particle is useful in many potential applications including drug delivery, biosensor, affinity separation, enzyme immobilization and soft actuators.
Novelty: Amphiphilic magnetic composite particle, useful in e.g. drug delivery, biosensor and affinity separation, comprises a core having hydrophobic polymer and magnetic nanoparticle, and a shell comprising hydrophilic nitrogen-containing polymer

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