natural deep eutectic vitrification solutions for cell, tissue, and organ banking
- 详细技术说明
- Application No.: 15/600,445This invention relates to the preservation and storage of biological materials and, in particular, to compositions and methods for the preservation and storage of biomolecules, cells, tissues and organs.
- *Abstract
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In one aspect, solvent systems are described herein. In some embodiments, such a solvent system comprises a disaccharide component, choline halide or choline acetate, and water. The water is present in the solvent system in an amount of 5 weight percent to less than 25 weight percent, and the solvent system is free of crystals. In another aspect, biomolecular compositions are described herein. Such a composition can comprise one or more biological molecules dissolved in a solvent system described herein. In yet another aspect, methods of storing a biological composition are described herein. In some instances, such a method comprises contacting the biological composition with a liquid preservative composition, wherein the liquid preservative composition comprises a solvent system or biomolecular composition described herein.
- 国家/地区
- 美国
