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Integrated Microsystem for Detection of Proteins in Liquid Solution

详细技术说明

This microfluidics bio-sensor is an acoustic wave-based, sensor system incorporating functionalized nanotubes that accurately measures biomolecules present in low picomolar concentrations in a sample as small as 10 µl.  This miniature, integrated system can instantaneously measure blood-borne biomarkers linked to diseases, like cancers, and to disease progression.

*Abstract

Numerous biomarkers are now available for identification of complex and heterogenic diseases, such as cancers, along with biomarkers that are linked to different stages of disease progression. For screening and disease identification, the clinical laboratory requires rapid, sensitive, accurate measurement of biomarkers in blood samples. Presently, enzyme-linked immunosorbent assays (ELISAs) using biomarker antibodies are the standard for clinical analysis of disease biomarkers. Although sensitive, ELISAs are slow and laborious, taking many hours to complete, requiring labeled, detection molecules and a significant amount of blood sample.

国家/地区

美国