Optically Driven Separations in Photonic Crystal Fibers
- 详细技术说明
- An efficient and practical method was discovered for separating microscopic particles over long distances using liquid core waveguiding photonic crystal fibers.
- *Abstract
-
Researchers at Cornell University have discovered an efficient and practical method for separating microscopic particles over long distances using liquid core waveguiding photonic crystal fibers. This optical chromatography method offers three orders of magnitude improvement in separation resolution than current bioanalytical techniques. While current optical methods require very large power sources (700mW) with only millimeter scale separations, Cornell's device uses significantly less power (10mW) and achieves a scale separation two orders of magnitude higher than competing devices.
This device has already been successfully integrated into a microfluidic architecture and demonstrated the ability to concentrate and separate micron sized particles with high resolution over long distances, a barrier which until recently has limited the practical uses of optical separation methods. These advancements provide an exciting new materials separation method for the research community, as well as an opportunity to develop new biomolecule and pathogen separation and detection systems.
Potential Applications
- Pathogen detection
- Liquid chromatography
Advantages
- Optically driven separation without phototoxicity
- Improved separation resolution
- Enhanced performance including ability to concentrate and separate micron sized particles
- Efficient process
- *Licensing
- Martin Teschlmt439@cornell.edu(607) 254-4454
- 其他
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- Mandal, S. & Erickson D. (2007). Optofluidic Transport in Liquid Core Waveguiding Structures. Applied Physics Letters, 90, 184103.
- Patent Application: 12/143,952;
- 国家/地区
- 美国
