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Novel Method for Accelerating Alimentary Tract Recovery in Post Abdominal Surgeries

详细技术说明

Researchers from UC San Diego have developed a method to attenuate postoperative intestinal complications (ileus). This technology provides techniques to reduce intestinal dysfunction including a lack of intestinal food transport by lack of peristalsis after intestinal ischemia, intestinal resections, and other surgical conditions associated with intestinal injury. This technology includes the use of serine protease inhibitors to reduce the postoperative ileus.

*Abstract

Ileus is the hypomotility of the gastrointestinal tract in the absence of mechanical bowel obstruction. Postoperative ileus occurs in approximately 50 percent of patients who undergo major abdominal surgery. The clinical consequences of postoperative ileus may be profound and increases medical costs due to prolonged hospital stays.

*IP Issue Date

Mar 29, 2016

*Principal Investigation

Name: Frank DeLano

Department:

Name: Darin Saltzman

Department:

Name: Geert Schmid-Schonbein

Department:

附加资料

Patent Number: US20140018293A1
Application Number: US13876943A
Inventor: Delano, Frank A. | Schmid-Schonbein, Geert W. | Saltzman, Darin
Priority Date: 2 Oct 2010
Priority Number: US20140018293A1
Application Date: 17 Sep 2013
Publication Date: 16 Jan 2014
IPC Current: A61K003838 | A61K0031195 | A61K0031497
US Class: 5140074
Assignee Applicant: The Regents of the University of California
Title: MINIMIZING INTESTINAL DYSFUNCTION
Usefulness: MINIMIZING INTESTINAL DYSFUNCTION
Summary: The methods are useful for treating ileus and abdominal dysfunction (all claimed); or for reducing symptoms associated with abdominal dysfunction or ileus following surgery or other abdominal episode.

主要类别

诊断/治疗

细分类别

其他疾病

申请号码

9295715

其他

Intellectual Property Info

Worldwide non-exclusive rights available; pending patents available under confidentiality.

Related Materials

Saltzman DJ, FA DeLano, GW Schmid-Schönbein (2010) Enteral and Peritoneal Blockade of Serine Proteolytic Enzymes Accelerates Post-Surgical Bowel Function Recovery. J Am Coll Surg, Vol. 211 (3S) September 2010. (2010 Clinical Congress of the American College of Surgeons. October 3-7, 2010. Washington, DC, USA)

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• Preventing Breakdown of Tissues in Shock and Multi-Organ Failure

Tech ID/UC Case

21886/2011-054-0

Related Cases

2011-054-0

国家/地区

美国