Transposon Vector for Vertebrate & Invertebrate Genetic Manipulation
- 技术优势
- Various types of vectors – introduce transposons to targeted areas in different organisms Successful creation of transgenic animals – genetic transformations in vertebrate and invertebrate cells
- 技术应用
- Research tool for transgenic technology – produce therapeutic proteins or disrupt gene function, e.g. transform mosquito genes to minimize spread of arboviral diseaseGene therapy – alter genes to treat or prevent genetic problems
- 详细技术说明
- None
- *Abstract
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Background:
Therapeutic delivery of genes is a rapidly evolving technique used to treat or prevent a disease at the root of the problem. The global transgenic market is currently $24B, growing at an annual projected rate of 10%. Currently, a variation of this technique is widely used on animals and crops for production of desirable proteins, but this is a heavily infiltrated market. Thus, entering the gene therapy segment is more promising and would enhance the growth of this industry.
Brief Description:
UCR Researchers have identified a novel transposon from Aedes aegypti mosquitoes. This mobile DNA sequence can insert itself into various functional genes to either cause or reverse mutations. They have successfully developed a transposon vector system that can be used in both unicellular & multicellular organisms, which can offer notable insight to improve current transgenic technologies as well as methods of gene therapy.
- *Applications
-
- Research tool for transgenic technology – produce therapeutic proteins or disrupt gene function, e.g. transform mosquito genes to minimize spread of arboviral disease
- Gene therapy – alter genes to treat or prevent genetic problems
- *IP Issue Date
- Oct 17, 2017
- *Principal Investigation
-
Name: Peter Atkinson
Department:
Name: Kun Liu
Department:
Name: Susan Wessler
Department:
- 申请号码
- 9790477
- 其他
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Images
Photo by NIH
Tech ID/UC Case
25287/2012-608-0
Related Cases
2012-608-0
- 国家/地区
- 美国
