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A Microfluidic Dynamic Vapor Control System

技术应用: This device is useful for small volume assays such as protein crystallization.

详细技术说明: University researchers have developed a small, integrated system to dynamically change the chemistry of a small drop by controlling the vapor. This system uses microfluidic vapor lines and on-board vapor reservoirs that can be actuated to produce vapor on demand. It also identifies storing the reagents or materials needed to generate the vapor on the same device for a convenient, disposable cartridge.

*Abstract: Controlling the chemistry of small drops is troublesome owing to the difficulty in handling and metering small volumes. To change the chemistry of a 50nl drop by 10% would require adding or removing a 5nl quantity - very difficult. As a result, most nanovolume assays are set up once and never modified afterwards. Large environmental systems have been built to provide vapor controlled change of chemistry. However, these are far too bulky and inconvenient to be of use to a typical researcher and have seldom been used in nanovolume assays.

*Principal Investigation: Name: Mark Bachman
Department:

Name: Guann Pyng Li
Department:

Name: Liang (Lilly) Wu
Department:

附加资料: Patent Number: US7811443B2
Application Number: US2004967913A
Inventor: Bachman, Mark | Li, Guann-Pyng | Wu, Liang
Priority Date: 16 Oct 2003
Priority Number: US7811443B2
Application Date: 18 Oct 2004
Publication Date: 12 Oct 2010
IPC Current: B01D000342
US Class: 205687 | 203099 | 204450
Assignee Applicant: The Regents of the University of California
Title: Microfluidic dynamic vapor control system
Usefulness: Microfluidic dynamic vapor control system
Summary: Used for changing the chemical composition of small drops (420).

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