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Methods For Differentiating Insulin-producing Beta Cells from Pancreatic Precursor Cells

技术优势
No need to rely on insulin producing cells isolated from the limited donorsPossibility of selecting the donor of the induced cells and thereby matching the recipientThe induced cells can be further manipulated to reduce immune rejectionThe cells to be implanted can be cultured and expanded to obtain necessary density for transplantationTransplant procedure is very similar to the pancreatic islets implantation protocolMuch shorter scheme to regenerate insulin producing cells, compared to therapy based on stem cells
技术应用
Treatment of Type 1 diabetes due to the body's failure to produce insulinTreatment of Type 2 diabetes due to the body's diminished response to insulinThe factors responsible for differentiation can be used to grow beta cells
详细技术说明
The technology presents a new method to grow insulin producing beta cells from pancreatic precursor cells. Factors that can direct the differentiation of non-insulin-producing precursor cells into insulin producing beta cells were found. The precurso...
*Abstract
None
*Inquiry
Sara GusikColumbia Technology VenturesTel: (212) 854-8444Email: TechTransfer@columbia.edu
*IR
2026
*Principal Investigation
*Web Links
WIPO: WO/2008/063934
国家/地区
美国

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