Development of Anti-angiogenic miRNA Therapeutics for Corneal Neovascularization
- 详细技术说明
- This new technology includes two novel inventions: 1) discovery of miRNAs that influence the neovascularization of the cornea and 2) optimization of rAAV gene therapy method for specific delivery to t
- *Abstract
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This new technology includes two novel inventions: 1) discovery of miRNAs that influence the neovascularization of the cornea and 2) optimization of rAAV gene therapy method for specific delivery to the cornea. Neovascularization is the most common corneal pathological condition and underestimated cause of blindness. Injection of the rAAV constructs that include synthetic nucleic acids that mimic or inhibit the discovered miRNA can reduce corneal neovascularization in mice.
- *IP Issue Date
- None
- *IP Type
- Other Patent
- 国家
- Not Available
- 申请号码
- None
- 国家/地区
- 美国
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