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Agrobacterium Strain for Higher Plant Quality

总结: Researchers at Purdue University have developed a system to generate transgenic plants with low transgene copy numbers and have almost eliminated the presence of T-DNA binary backbone sequences in these plants. This system will be very useful for the transformation of plants and offers improved quality of transformed plants, without regulatory issues or inhibiting gene expression.

技术应用: Industrial biotechnology Improving the quality of transgenic plants Academic research

*Background: For decades, a major goal of scientists working inagricultural biotechnology has been to design transgenic plants with lowtransgene copy numbers and no T-DNA vector backbone integration. T-DNA vectorbackbones usually harbor bacterial antibiotic resistance genes, leading to avariety of regulatory issues. Also, plants with high transgene copy numberswill often silence the expression of important genes. Current methods generatea large number of transgenic plants, subject them to a variety of tests, andthen discard those with multiple transgenes and vector backbone sequences.These methods are both time consuming and expensive.

*Web Links: Purdue Office of Technology CommercializationPurdueInnovation and EntrepreneurshipStanton GelvinPurdue Biological Sciences

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