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Cardiomyopathy TreatmentA new class of oligonucleotides can be used to treat cardiomyopathy. The short, protein-interacting DNAs and RNAs (SPIDRs) are designed to selectively bind to phospholamban (PLN), a compound that inhibits SERCA, which is a necessary function for cardiac health.Results show th..... [更多]
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Autologous T cells are currently being investigated for use in adoptive immunotherapy to treat cancer and infectious diseases. Existing methods to culture, expand, and activate T cells utilize ligands immobilized on stiff surfaces. However, the mechanical properties of culture surfaces influence cel..... [更多]
Researchers at Nationwide Children’s Hospital have found that exosomes from healthy cells contain molecular signals reflective of a healthy state and can be delivered to fibrotic cells that mitigate or reverse fibrosis. [更多]
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