Unlike previously reported induction procedures, the present methods utilize a novel small molecule-based approach to derive human CECs along with three major retinal cell types, RPE, photoreceptor and RGC, from PSCs in a directional fate restriction fashion. Moreover, using EFSC-derived NCSCs as a .....
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Vascularization remains a critical challenge in tissue engineering and regenerative medicine. In order to be able to engineer anatomically-sized tissues, a functional vascular network is needed to overcome the limitations of diffusion-based nutrient transport. However, existing methods for vascular .....
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The high-voltage charge pump represents an important advance in reducing the footprint of portable and other electronic devices. Its innovative design enables the use of high-density, low-voltage pumping capacitors, which require significantly less area than the high-voltage pumping capacitors of co.....
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Recently scientists developed a novel type of self-assembled porous crystalline materials, constructed of metal clusters and organic linkers, named metal organic frameworks (MOFs). These materials were designed to provide regular-pores sorbents with an adjustable size of cavities, channels, and aper.....
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Magnetic resonance spectroscopy (MRS) is a powerful tool for biomedical research and clinical diagnostic, allowing for non-invasive measurement and quantification of chemical compounds from living tissues. However, currently available MRS processing and quantification software are limited in their p.....
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