Osteoporosis, a silent disease, is a skeletal disorder characterized by compromised bone strength predisposing to an increased risk of fractures. The global burden of osteoporosis is significant nowadays – over 200 million people worldwide and approximately 30% of all postmenopausal women in the USA.....
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The ability of cancer cells to acquire resistance to multiple drugs, termed multidrug resistance (MDR), is often mediated by overexpression of ATP-binding cassette (ABC) transporters that remove substrates out of the cell against a concentration gradient. Among 48 human ABC transporters discovered, .....
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Most traditional methods for T1 map estimation in MR imaging with Fast Low Angle Shot (FLASH) sequences are aimed at high efficiency by compromising the fitting accuracy. In this paper, the fundamental problem of parameter estimation in FLASH MRI was re-examined, and an accurate and fast optimizati.....
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