Described are nucleic acid aptamers that are able to bind to and inhibit the function of sclerostin, which is an important negative regulator of bone growth. The aptamers have application as therapeutics for diseases of bone including osteoporosis, osteopenia, osteoarthritis and other osteoporosis-r.....
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Methods And Systems Are Provided That May Be Used To Utilize And Manufacture A Light Sources Apparatus. A First Light Emitting Diode Emits Light Having A First Wavelength, And A Second Light Emitting Diode For Emitting Light Having A Second Wavelength. Each Of The First And Second Light Emitting Dio.....
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A Bioengineered Ivd For Disc Replacement Has Been Developed That Has Mechanical And Structural Support Characteristics Similar To Those Of Native Ivd. Extracellular Matrix (Ecm) Provides Support To Living Cell Components And Interacts With The Living Cellular Components During The Fabrication Proces.....
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Diastereoselective Epoxidation Of Allylically Substituted Alkenes Using Metalloporphyrins As Catalyst Provides High Trans-Selectivities (I.E., Trans-:Cis-Epoxide Ratio). A Diversity Of Cycloalkenes Bearing Different Allylic Substituents Are Shown To Be Efficiently Epoxidized To Afford The Correspond.....
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