Although early programs targeting MMPs (matrix metalloproteins) were largely unsuccessful due to adverse side effects, they remain a viable and highly desirable therapeutic target. The main obstacle in the attempts to target MMPs is the ability to selectively target individual family members. The pr.....
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Streptococcus pneumoniae (S. pneumonia) is part of the flora of the human respiratory tract, and can cause mucosal and invasive infections such as otitis media, pneumonia, sepsis and meningitis. The mucosal epithelial surfaces, with their tight junctions, constitute the first line of defense that pr.....
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A monoclonal antibody against GluR3B, a peptide found in epilepsy patients, and especially in patients suffering from intractable, resistant forms of the disease, could be used in diagnosis kits as well as in drug development for this form of "autoimmune epilepsy".
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