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Highlights:The World Health Organisation predicts that by 2040, as a result of a growing ageing population, neurodegenerative diseases (NDDs) will have overtaken cancer to become the world’s second leading cause of death, after cardiovascular disease. However, governments and industry have yet to ma..... [更多]
Interleukin 17 (IL-17) represents a family of pro-inflammatory cytokines consisting of six members, termed IL-17A-F. IL-17A is expressed by a unique lineage of CD4 T cells (Th-17) and is known to stimulate fibroblasts, endothelial cells, epithelial cells and macrophages to produce multiple pro-infla..... [更多]
Scientists at the Weizmann Institute of Science describe a novel oligonucleotide, also known as an Aptamer, which has been designed to complement the receptor-binding region of the influenza haemagglutinin molecule. It was constructed by screening a DNA library and processing by the SELEX procedure...... [更多]
A subchondral defect is usually characterized by a structural breakdown of the articular cartilage and the bone underneath due to trauma or disease, leading to chronic disabilities. Treating such defects is an important medical target since in the adult patient, damaged cartilage cannot spontaneousl..... [更多]
Additional material on the technology can be supplied upon request [更多]
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