ER stress, elicited by chemotherapeutic agents such as doxorubicin, 5FU, vincristine and bortezomib, or statins such simvastatin, triggers cell death at least in part through generation of leukotriene C4 (LTC4), which induces ROS accumulation, DNA damage and subsequent cell death. LTC4 can be produc.....
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SoE MT (also known as coarse-grained MT and block MT) processors run multiple threads on a pipeline machine, while the pipeline switches threads on stall events (e.g., cache miss). The thread switch penalty is determined by the number of stages in the pipeline that are flushed with in-flight instruc.....
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Bladder cancer is a common malignancy; it is the 4th most common cancer in males and the 9th in females. The presenting symptom is usually blood in the urine, and diagnosis is currently based on cystoscopy, which is invasive, costly, painful and time consuming. To date, no biomarker has been ident.....
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A novel desulfurization system achieves removal of sulfur dioxide (SO2) from industrial exhaust streams at efficiencies that can greatly supersede technologies currently in use. The chemical process is highly selective to SO2, and consumes much less reagents, therefore reducing the cost of desulfuri.....
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