There is a strong need for novel selective and safe approaches for the management of Alzheimer's disease.Development of selective bi-functional small molecules aimed to simultaneously inhibit beta- and gamma secretases in order to reduce amyloid-beta (Aβ) while avoiding toxic effects of full enzymat.....
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Carbon Nanotubes (CNT) have fascinating properties and have been attracting scientific as well as technological attention in the last few years. Their superb mechanical properties make them desirable as reinforcing fillers in polymeric matrices forming light weight super strong meso-composits. One f.....
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Intraocular pressure (IOP), an important part of any eye exam, is measured with a special instrument called a tonometer. The most widely employed devices are the Goldmann and the air-puff tonometers. In both, the intraocular pressure is inferred from the force required to flatten (applanate) a const.....
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Lysosomal Storage diseases (LSD) are inherited genetic defects, resulting in an enzyme deficiency.This deficiency prevents the lysosome from metabolizing cellular waste, and results in their accumulation in the cell. Excessive storage of proteins, saccharides and/or fats can cause permanent cellular.....
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Background:Stirling cycle-based cryocoolers employ mechanical compressors activated by inductive electrical motors producing an oscillating pressure in a gas. The main disadvantage of these conventional compressors is their limited lifetime, caused by mechanical friction and wear. Wear products degr.....
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