We have developed an ELISA-based immunoassay that measures the levels of two proteins in the blood, Mortalin/GRP75 and HSP70, identifying colorectal cancer patients at high risk of poor survival.Mortalin/GRP75, is a ubiquitous mitochondrial chaperone related to the cytosolic heat shock protein 70 (H.....
[更多]
VoIP systems, a standard in modern communication, are troubled by unreliability in the communication channel such as the internet. Data losses are frequent and can render audio signals incoherent. Current methods for filling in missing parts rely on plain interpolation and insertion of noise. More a.....
[更多]
Animal models of human diseases of the CNS occupy a central role in drug discovery yet these models fail to yield new insights and efficacious drugs for the treatment of these diseases, in a field having a collective economic cost of over $40 billion per year. The number of CNS drugs reaching approv.....
[更多]
ER stress, elicited by chemotherapeutic agents such as doxorubicin, 5FU, vincristine and bortezomib, or statins such simvastatin, triggers cell death at least in part through generation of leukotriene C4 (LTC4), which induces ROS accumulation, DNA damage and subsequent cell death. LTC4 can be produc.....
[更多]
Monoclonal antibodies specific to cholesterol/ceramide mixture Description: Monoclonal antibodies specific for cholesterol/ceramide-rich domains (clones 405F, 14F, 499F) and cholesterol micro-domains (clones 36A1, 5881) in cell membranes. Originally raised against an artificial monolayer of lipid mi.....
[更多]
| |< <- | [42] [43] [44] [45] [46] [47] [48] [49] [50] [51] [52] | -> >| |
