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Highlights:p53, the most important tumour suppressor protein in the cell, is a homotetrameric protein that has a pivotal role in the cellular anti cancer defense mechanism.p53 is active as a tetramer: the tetramer binds DNA much tighter than the monomer / dimer and is retained in the nucleus while t..... [更多]
The geometry of crystals, bones and other natural objects can appear random. But they possess characteristic patterns which help attain beneficial features, such as aesthetics or structural strength. It is possible to generate such patterns in 2D, using a sample pattern for reference. These methods ..... [更多]
A method to produce amides in one step without any unwanted by-products, by coupling of alcohols with amines with the liberation of hydrogen gas, catalyzed by unique ruthenium complexes.Amides are widely used in the industry (e.g. nylon, Kevlar) and have widespread importance in biochemical and chem..... [更多]
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