Since HIF-2alpha is too labile to be used as a marker, ADORA2A instead can be used as readout of HIF-2alpha activation and can be easily measured at the RNA level in biopsy samples.
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Introduction Lumbar fusion surgery is used for a variety of lumbar spine problems. Initially, most lumbar spine problems are treated conservatively. If symptoms persist, some individuals may be candidates for lumbar spine fusion surgery. The goal of such surgery is to relieve pain, numbness, and wea.....
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§ Identifies a unique mechanism of protecting ubiquitin-modified fusion proteins § Stabilizes the binding partner of the fusion protein and also protects it from degradation § Enables determination of ubiquitylated proteins § Allows for characterization of protein function after ubiquitylation .....
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